The Wellmen's scorers were Shaun Tuck (2), Steve Lewis (2), Graeme Williams and Danny Desormeaux, his first goal in a Holywell Town shirt.
Reserve Team players Owen Davies and Jake Cooke both made their first team debut's and both had a great game.
Manager John Haseldin added, "We played some good football this afternoon on a tight pitch. Also, well done to Jake Cooke and Owen Davies on their 1st team debut's and both did well.
I'm glad we took the game with Prestatyn Sports, I think they will do well this season and good luck to them."
The Wellmen next face Conwy Borough on Saturday at Y Morfa, kick off 2.30pm
Thanks to Clint (The 94th Minute) for the picture.